Softgels
Sirio Pharma is a global leader in nutraceutical softgel manufacturing, offering custom formulations, advanced R&D, and end-to-end CDMO services for top supplement brands. With cutting-edge U.S. softgel manufacturing and a global network,
we deliver innovative products with speed, scale, and pharmaceutical-grade quality standards. We specialize in a full range of softgel dosage forms, including:
• Gelatin softgels for oils, botanicals, and vitamins
• Plant-based softgels with clean-label, vegan shells
• Enteric-coated softgels for targeted delivery
• Plantegrity™ softgels for superior clarity and performance
• Custom colors, shapes, and branding for stronger shelf presence
Softgel Technology
Our softgel technologies offer a range of shell systems to match formulation needs, label preferences, and performance goals. We provide classic gelatin softgels alongside plant-forward options like Plantegrity™ carrageenan-based formulas and Plantegrity™ gellan gum systems, as well as tapioca softgels for alternative sourcing and positioning. For targeted delivery and enhanced consumer experience, EnteriClear™ softgels are engineered to support specialized release and protection where needed.
Ingredient Types
We support a wide range of ingredient types engineered for stability, performance, and strong consumer positioning. Our capabilities include omega-3/fish oils and botanical oils, as well as sensitive actives like probiotics/enzymes that require careful handling. We also develop solutions for high-heat shipping environments, natural branding goals, and challenging formats containing high-oxidation actives, helping protect freshness, potency, and shelf life from production through delivery.
Engineered for Global Markets
These systems are ideal for a variety of product goals and market demands—from omegas, botanicals, and fat-soluble ADEK vitamins to premium plant-based formulas that support modern label preferences. They’re also well-suited for global shipping and tropical markets, where heat and transit conditions can challenge stability, and for natural-positioned brands focused on clean, recognizable formats. For more sensitive applications, they can support probiotics, enzymes, and reflux-sensitive oils, helping improve protection, comfort, and overall consumer experience.
Ready to scope your softgel project?