Global Company History
Started production of nutraceutical gummies, tablets, capsules and powders.
First entity in China to receive the NPA dietary supplements GMP certificate.
Opened US Branch
Began production of functional beverages
• Ranked as the largest Chinese nutritional supplements exporter
• Began production of vegetarian softgels and probiotics products
Established the Ma'anshan Health Industrial Park
Acquisition of Ayanda, Germany: GMP-certified CDMO for nutraceutical and pharmaceutical softgels, serving customers in Europe and the global market for over 25 years.
Approval of CNAS certification
• Neutraceutical gummy production begins at Ma’anshan plant
• Inauguration of new R&D laboratory of 2600 m² at Shantou
• Inauguration of a workshop dedicated to probiotic dosage forms at Shantou
• European patent awarded to Ayanda for a softgel containing probiotics and omega 3
• Sirio listed on the Shenzhen Stock Exchange, as first food supplement CDMO ever
• Inauguration of a new office in Shanghai
• Capacity expansion of German Ayanda plant, including equipment for vegetarian softgels
• At the Ma’anshan plant: Inauguration of new 1200 m² large R&D centre and increase of capacity for manufacturing powders, liquids and jellies
• Established the Shanghai R&D Center
• Ma'anshan Smart Warehouse Commenced Operations
• Acquisition of Best Formulation, USA
• Full integration of Ayanda GmbH into SIRIO Europe
• Zhuhai Bonded Factory Commenced Operations
• New fully automated packaging line launched in Germany
• Coenzyme Q10 gummy standard listed in the United States Pharmacopeia (USP)
• E-type bioequivalence enhancement platform officially released
Global Locations
Dedicated to serving global customers, Sirio operates 7 advanced automated manufacturing sites and 5 R&D centers worldwide. Moreover, through strategic partnerships with leading international brands, we have steadily expanded our global footprint. As a result, we have established ourselves as one of the most influential players in nutraceutical contract manufacturing.
About the Shantou Facility
As the global headquarters of Sirio Pharma, our flagship facility spans over 30,000 square meters and integrates lean production, automation, and digital intelligence.- With 18 smart production lines, our softgel facility increases output by 40% and cuts lead time by 35%, enabling faster, larger‑scale delivery. This also enhances efficiency and ensures greater flexibility in meeting diverse customer needs.
- CNAS-accredited, our advanced lab supports 2,000+ test methods and delivers a 99% self-inspection rate for food products.
- With strong energy management and water reuse systems, we drive sustainable and eco-friendly nutraceutical contract manufacturing.
Production Capabilities
Shantou Park I: Softgels, Tablets, Capsules, Functional drinks
Shantou Park II: Chewable Gels, Gel Strips, flavor burst beads
Related Certifications
BRCGS, TGA, NPAUL, UL 21 CFR Part 111, ISO9001, ISO14001, ISO45001, ISO45001 NSF, AEO, HACCP, Sedex, CNAS, USDA Organic, Animal OriginProducts Registered in EU. HCA-Halal, FOSAddresses
Shantou Industrial Park I No. 83 Taishan Road, Longhu District, Shantou, Guangdong, China Shantou Industrial Park IINo. 11 Zhuyenan Street, Huangshan Road, Longhu District, Shantou, Guangdong, ChinaAbout the Ma’anshan Facility
Spanning over 200,000 m², our intelligent manufacturing site integrates R&D and testing, production, and smart warehousing. It offers a fully integrated end-to-end solution from formulation to manufacturing and packaging.
- Flexible Manufacturing: Large-scale customization & small-batch agile turnaround
- Full-spectrum Quality Testing: 1,000+ test methods | 200+ custom internal standards | 99%+ self-inspection
- Digital Logistics Center: 45,000 m² smart facility | 70%+ boost in operational efficiency
Production Capabilities
Gummies, Tablets, Capsules, Powders, Functional drinks
Related Certifications
Addresses
1980 South Hongqi Rd, Yushan Dist., Ma’anshan, Anhui, ChinaAbout the Zhuhai Facility
Located in China’s first cross-border industrial zone—the Zhuhai-Macao Cross-border Industrial Park. This facility provides one-stop cross-border business support for global partners.- 7–14 Day Fast-track Delivery: Powered by cross-border infrastructure & policy advantages
- High-capacity intelligent manufacturing: Multi-million unit annual output
- Rapid Certification & Testing: Official COA & CNAS reports delivered efficiently
Production Capabilities
Softgels, Tablets, Capsules, Customized Nutrition Packs
Addresses
2nd & 4th Floors, Area A, Yinji Cross-border Complex Building, 37 Zhongxin Rd, Zhuhai Free Trade Zone, Xiangzhou, Zhuhai, Guangdong, ChinaAbout the Pritzwalk Facility
With over 30 years of experience in production and product development, our German facility is recognized as one of the top five softgel manufacturers in Europe. Moreover, it is renowned for expertise in complex formulations and advanced nutraceutical contract manufacturing.- Multidisciplinary Expert Team: From R&D to manufacturing and marketing
- Full-process quality control: Ensuring high-quality outcomes at every stage
- Sustainable Operations: Energy-efficient facilities + recovery systems for a greener future
Production Capabilities
Gummies, Softgels, Tablets
Related Certifications
Pharma GMP, IFS, BRCGS, FDA, FOS, MSC, Feed, Eu Organic Certification, Halal or KosherAddresses
Am Hunengrab 20 16928 Pritzwalk Brandenburg, GermanyAbout the USA Facility
A well‑established CDMO in the U.S. dietary supplement industry, Best Formulations is a trusted partner in nutraceutical contract manufacturing. In addition, it is a specialist in plant‑based softgel manufacturing. The company has over 40 years of experience in product development and production.- Expert R&D Team: Supporting clients with formulation innovation
- End-to-end Quality Management: Ensuring high-quality, reliable product output
- Flexible Packaging Capabilities: High-speed bottling lines & tablet pouching services
Production Capabilities
Gummies, Softgels, Tablets, Capsules, Powders
Related Certifications
NSF-455-2 GMP for Dietary supplement, NSF Sport, USDA Organic Certification, SMETA, lSO 22716 for Personal Care Facility
