Scroll Top

Global Company History

1993
Sirio Founded
1999
Start Dietary Supplement Manufacturing
2002
Oversea Business Founded
2003
Gain GMP Certification
Start USA/EU Market
2007
Started production of nutraceutical gummies, tablets, capsules and powders.
2009
First entity in China to receive the NPA dietary supplements GMP certificate.
2010
Opened US Branch
2012
Began production of functional beverages
2013
Ranked as the largest Chinese nutritional supplements exporter
Began production of vegetarian softgels and probiotics products
2015
Established the Ma'anshan Health Industrial Park
2016
Acquisition of Ayanda, Germany: GMP-certified CDMO for nutraceutical and pharmaceutical softgels, serving customers in Europe and the global market for over 25 years.
 
2017
Approval of CNAS certification
2018
Neutraceutical gummy production begins at Ma’anshan plant

Inauguration of new R&D laboratory of 2600 m² at Shantou
2019
Inauguration of a workshop dedicated to probiotic dosage forms at Shantou
European patent awarded to Ayanda for a softgel containing probiotics and omega 3
Sirio listed on the Shenzhen Stock Exchange, as first food supplement CDMO ever
Inauguration of a new office in Shanghai
2020
Capacity expansion of German Ayanda plant, including equipment for vegetarian softgels
At the Ma’anshan plant: Inauguration of new 1200 m² large R&D centre and increase of capacity for manufacturing powders, liquids and jellies
2022
Established the Shanghai R&D Center
Ma'anshan Smart Warehouse Commenced Operations
2023
Acquisition of Best Formulation, USA
Full integration of Ayanda GmbH into SIRIO Europe
Zhuhai Bonded Factory Commenced Operations
2024
New fully automated packaging line launched in Germany
Coenzyme Q10 gummy standard listed in the United States Pharmacopeia (USP)
E-type bioequivalence enhancement platform officially released

Global Locations

Dedicated to serving global customers, Sirio operates 7 advanced automated manufacturing sites and 5 R&D centers worldwide. Moreover, through strategic partnerships with leading international brands, we have steadily expanded our global footprint. As a result, we have established ourselves as one of the most influential players in nutraceutical contract manufacturing.

About the Shantou Facility
As the global headquarters of Sirio Pharma, our flagship facility spans over 30,000 square meters and integrates lean production, automation, and digital intelligence.
Recognized in 2023 as a national‑level Green Factory, this site is the largest softgel manufacturing base within Sirio. It offers a comprehensive range of dosage forms — including plant‑based softgels, enteric‑coated softgels, and chewable softgels.
Production Capabilities

Shantou Park I: Softgels, Tablets, Capsules, Functional drinks

Shantou Park II: Chewable Gels, Gel Strips, flavor burst beads

Related Certifications
BRCGS, TGA, NPAUL, UL 21 CFR Part 111, ISO9001, ISO14001, ISO45001, ISO45001 NSF, AEO, HACCP, Sedex, CNAS, USDA Organic, Animal OriginProducts Registered in EU. HCA-Halal, FOS
Addresses
Shantou Industrial Park I No. 83 Taishan Road, Longhu District, Shantou, Guangdong, China Shantou Industrial Park IINo. 11 Zhuyenan Street, Huangshan Road, Longhu District, Shantou, Guangdong, China
About the Ma’anshan Facility

Spanning over 200,000 m², our intelligent manufacturing site integrates R&D and testing, production, and smart warehousing. It offers a fully integrated end-to-end solution from formulation to manufacturing and packaging.

Equipped with advanced R&D laboratories and a comprehensive testing center, the facility focuses on the development of nutritional gummies, functional beverages, and powder formulations. In 2023, it was recognized as both a “Smart Factory” and a “Green Factory” by Anhui Province, underscoring its leadership in intelligent and sustainable nutraceutical contract manufacturing.
Production Capabilities

Gummies, Tablets, Capsules, Powders, Functional drinks

Related Certifications
BRCGS, HACCP, ISO9001, NPA, UL, NSF, ISO14001, ISO45001, ISO50001, ISO27001, USDA Organic, Indonesian Halal, Eu Organic Certification
Addresses
1980 South Hongqi Rd, Yushan Dist., Ma’anshan, Anhui, China
About the Zhuhai Facility
Located in China’s first cross-border industrial zone—the Zhuhai-Macao Cross-border Industrial Park. This facility provides one-stop cross-border business support for global partners.
Working in close collaboration with Sirio Pharma’s global nutraceutical contract manufacturing network, the Zhuhai site integrates procurement, logistics, R&D, production, packaging, and regulatory services. Its mission is to serve as a global delivery hub for nutrition, offering agile, full‑spectrum support for international health and wellness brands.
Production Capabilities

Softgels, Tablets, Capsules, Customized Nutrition Packs

Addresses
2nd & 4th Floors, Area A, Yinji Cross-border Complex Building, 37 Zhongxin Rd, Zhuhai Free Trade Zone, Xiangzhou, Zhuhai, Guangdong, China
About the Pritzwalk Facility
With over 30 years of experience in production and product development, our German facility is recognized as one of the top five softgel manufacturers in Europe. Moreover, it is renowned for expertise in complex formulations and advanced nutraceutical contract manufacturing.
In October 2024, two brand‑new automated packaging lines were officially launched, marking a significant milestone.Furthermore, the facility now delivers a fully integrated, end‑to‑end service. This covers formulation development, supplement manufacturing, and final pharmaceutical packaging.
Production Capabilities

Gummies, Softgels, Tablets

Related Certifications
Pharma GMP, IFS, BRCGS, FDA, FOS, MSC, Feed, Eu Organic Certification, Halal or Kosher
Addresses
Am Hunengrab 20 16928 Pritzwalk Brandenburg, Germany
About the USA Facility
A well‑established CDMO in the U.S. dietary supplement industry, Best Formulations is a trusted partner in nutraceutical contract manufacturing. In addition, it is a specialist in plant‑based softgel manufacturing. The company has over 40 years of experience in product development and production.
Backed by a dedicated team of gummy formulation experts and advanced precision equipment.  Best Formulations provides end‑to‑end gummy manufacturing and contract manufacturing services for global nutrition brands.
Our capabilities include heat‑stable gelatin gummies, plant‑based gummies, sugar‑free formulas, and multi‑active complex formulations. Moreover, we deliver innovation and reliability for forward‑looking nutrition brands.
Production Capabilities

Gummies, Softgels, Tablets, Capsules, Powders

Related Certifications

NSF-455-2 GMP for Dietary supplement, NSF Sport, USDA Organic Certification, SMETA, lSO 22716 for Personal Care Facility

Addresses
17758 Rowland St, City of Industry, CA 91748, USA
Thailand Facility in 2027
Covering approximately 60,000 square meters, the industrial park will include a gummy production workshop, warehouses, a power center, and other supporting facilities. Upon its completion and planned operational launch in 2027, it will have an annual production capacity of 2.4 billion gummies.
Translate »